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If prompt rebound has not occurred during combined HYDREA and irradiation therapy, irradiation may also be interrupted. Instead, go back to your regular dosing schedule and check with your doctor. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your health care professional. Before using this medicine, consult your doctor or pharmacist if you have: low white blood cell count, low blood clotting cells platelets severely low red blood cells anemia. The amount of Hydrea that you will receive depends on many factors, including your height and hydrea non medico weight, your general health or other health problems, and the type of cancer or condition being treated. Gov Identifier: NCT00006400 Purpose The purpose of this study is to determine if hydroxyurea therapy is effective in the prevention of chronic end organ damage in pediatric patients with sickle cell anemia. The morphologic change resembles pernicious anemia, but is not related to vitamin B12 or folic acid deficiency.